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HSP90AA1信息

英文名称:Heat shock protein HSP 90-alpha
中文名称:热休克蛋白90α家族A类成员1
靶点别称:Heat Shock Protein 90kDa Alpha (Cytosolic), Class A Member 1,Heat Shock 90kDa Protein 1, Alpha,Heat Shock 90kD Protein 1, Alpha,HSP 86,HSP90A,HSPC1,Heat Shock Protein 90kDa Alpha Family Class A Member 1,Epididymis Secretory Sperm Binding Protein Li 65p,Epididymis Luminal Secretory Protein 52,Heat Shock 90kD Protein 1, Alpha-Like 4,Heat Shock 90kD Protein, Alpha-Like 4,HEL-S-65p,FLJ31884,HSPCAL1,HSPCAL4,HSP89A,HSP90N,Hsp103,Hsp89,Hsp90,EL52,HSPN,LAP2,Heat shock protein HSP 90-alpha,HSP86,LPS-asso
上市药物数量:1
临床药物数量:0
最高研发阶段:批准上市

HSP90AA1产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
HS1-H513x
Human
Human HSP90AA1 / HSP86 Protein, GST Tag
ACRO质量管理体系
 
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HSP90AA1分子别名

HSP90AA1,HSP90A,HSP 86,HSP86,HSPC1,HSPCA,EL52,HSP89A,HSP90N,HSPCAL1,HSPCAL4,HSPN,Hsp89,Hsp90,LAP2

HSP90AA1分子背景

Heat shock protein HSP 90-alpha (HSP90AA1 or HSP90A) is also known as Heat shock 86 kDa (HSP 86 or HSP86), Renal carcinoma antigen NY-REN-38, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2, which belongs to the heat shock protein 90 family. HSP90AA1 undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. HSP90AA1 interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

HSP90AA1上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验
Pimitespib TAS-116 批准上市 大鹏药品工业株式会社, 大冢制药株式会社 Jeselhy, ジェセリ Japan 胃肠道间质瘤 Taiho Pharmaceutical Co Ltd 2022-08-01 实体瘤, 胃癌, 结直肠癌, 胃肠道间质瘤, 胰腺导管癌, 肺泡软组织肉瘤, 非小细胞肺癌 详情

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