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 > 【Integrin alpha V beta 6】

Integrin alpha V beta 6信息

英文名称：Integrin alpha-V/beta-6
中文名称：整合素α-V/β-6复合体
靶点别称：
上市药物数量：0
临床药物数量：6
最高研发阶段：临床三期

Integrin alpha V beta 6产品列表

筛选结果
产品库
物种
标签
属性
标记
货号 物种 产品描述 蛋白结构 纯度 活性
IT6-H82E4
Human		 Biotinylated Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His,Avitag™&Tag Free (MALS verified)
IT6-C52W9
Cynomolgus		 Cynomolgus Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His Tag&Tag Free
IT6-M52W9
Mouse		 Mouse Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His Tag&Tag Free (MALS verified)
CHEK-ATP125
Human		 HEK293/Human Integrin alpha V beta 6 Stable Cell Line
IT6-H52E1
Human		 Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His Tag&Tag Free (MALS verified)
IT6-M52E3
Mouse & Human		 Mouse & Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His Tag&Tag Free (MALS verified)
IT6-M82W9
Mouse		 Biotinylated Mouse Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His,Avitag™&Tag Free (MALS verified)
IT6-R52E6
Rat		 Rat Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His Tag&Tag Free (MALS verified)
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评论(4)
IT6-H82E4|Biotinylated Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His,Avitag™&Tag Free (MALS verified)
  1. 475XXXXXXX
    2. 3人赞
  2. Great communication from the Acro team--quickly received an email detailing the estimated delivery timeframe and asking if that timeframe was acceptable. Product was ready per the timeline provided by the Acro biosystems team and shipped. This was a new product for us (though we’ve used other acro biosystems products previously) and worked well for our intended use with Surface Plasmon Resonance (SPR). Thank you all!
  3. 2022-04-02
IT6-M52E3|Mouse & Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His Tag&Tag Free (MALS verified)
  1. 151XXXXXXX0
    2. 0人赞
  2. 物流速度很快，从北京发货，第二天就到了。选择用本产品用于筛选抗体和亲和力测定。目前只做了筛选工作，包被1ug/ml曲线响应良好。产品质量好！后续有需要还会在这里购买。
  3. >
  4. 2024-09-04
IT6-H52E1|Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, His Tag&Tag Free (MALS verified)
  1. 151XXXXXXX0
    2. 0人赞
  2. 产品在包被10ug/ml使用起来非常可靠，实验结果也出来漂亮的曲线，很稳定，很显著，非常清晰，重现性也好，不同的同事使用的效果基本相同！
  3. >
  4. 2024-09-06
查看更多评论
 

Integrin alpha V beta 6分子别名

Integrin alpha V beta 6,ITGAV&ITGB6

Integrin alpha V beta 6分子背景

Integrin alpha V beta 6 is a heterodimer of beta-6 associating with alpha-V. Integrin alpha-V beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. Also, Integrin alpha-V beta-6 acts as a receptor for coxsackievirus A9 and coxsackievirus B1 as well as herpes simplex virus-1/HHV-1. Furthermore, it binds the TGF-beta latency‑associated peptide (LAP) and activates TGF-beta 1 or TGF-beta 3 from large latent complexes. This activation requires interaction with LTBP-1 and fibronectin, and is enhanced by PAR-1.

Integrin alpha V beta 6临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Bexotegrast PLN-74809 临床三期 Pliant Therapeutics Inc 特发性肺纤维化, 新型冠状病毒感染, 成人呼吸窘迫综合征, 原发性硬化性胆管炎 详情
IDL-2965 IDL-2965 临床二期 Indalo Therapeutics Inc 非酒精性脂肪性肝炎, 特发性肺纤维化 详情
Nesvategrast OTT-166(OcuTerra Therapeutics); SF-0166 临床二期 Scifluor Life Sciences Inc, OcuTerra Therapeutics Inc 糖尿病黄斑水肿, 糖尿病视网膜病变, 年龄相关性黄斑变性 详情
18F-αvβ6-Binding-Peptide 18F-αvβ6-BP 临床一期 美国国立癌症研究所, 美国国立卫生研究院 直肠癌, 结肠癌, 新型冠状病毒感染, 胰腺癌, 乳腺癌, 结直肠癌, 冠状病毒科感染, 肺癌, 转移性乳腺癌 详情
[18F]FP-R01-MG [18F]FP-R01-MG; [18F]FP-R01-MG-F2 临床一期 Pliant Therapeutics Inc, 斯坦福大学, 中国医学科学院北京协和医学院 小细胞肺癌, 特发性肺纤维化, 新型冠状病毒感染, 胰腺癌, 原发性硬化性胆管炎, 脑转移, 肺癌, 非小细胞肺癌 详情
Ga-68-Trivehexin RAD-301 临床一期 Trimt GmbH 胰腺癌, 胰腺导管癌 详情

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