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 > 【NKp46】

NKp46信息

英文名称：Natural cytotoxicity triggering receptor 1
中文名称：
靶点别称：NK cell-activating receptor，NK-p46，Lymphocyte antigen 94 homolog，NKp46，hNKp46，Lymphocyte Antigen 94 Homolog (Activating NK-Receptor; NK-P46)，Natural killer cell p46-related protein，LY94，Lymphocyte Antigen 94 (Mouse) Homolog (Activating NK-Receptor; NK-P46)，CD335 Antigen，CD335
上市药物数量：0
临床药物数量：3
最高研发阶段：临床二期

NKp46产品列表

筛选结果
产品库
物种
标签
属性
标记
货号 物种 产品描述 蛋白结构 纯度 活性
NC1-H52H4
Human		 Human NKp46 / NCR1 / CD335 Protein, His Tag (MALS verified)
NC1-H52H6
Human		 Human NKp46 / NCR1 / CD335 Protein, His Tag
NP6-H82H3
Human		 Biotinylated Human NKp46 Protein, His,Avitag™, premium grade
CEA-B040
Human		 ClinMax™ Human NKp46/NCR1 ELISA Kit, PRO
CHEK-ATP153
Human		 HEK293/Human NKp46 Stable Cell Line
NC1-C5255
Cynomolgus		 Cynomolgus NKp46 / NCR1 / CD335 Protein, Llama IgG2b Fc Tag, low endotoxin
NC1-C52H4
Cynomolgus		 Cynomolgus NKp46 / NCR1 / CD335 Protein, His Tag (MALS verified)
NC1-C82E5
Cynomolgus		 Biotinylated Cynomolgus NKp46 / NCR1 / CD335 Protein, His,Avitag™ (MALS verified)
NC1-H5255
Human		 Human NKp46 / NCR1 / CD335 Protein, Llama IgG2b Fc Tag, low endotoxin
NC1-H5257
Human		 Human NKp46 / NCR1 / CD335 Protein, Fc Tag, premium grade
NC1-H5258
Human		 Human NKp46 / NCR1 / CD335 Protein, Fc Tag
NC1-H5259
Human		 Human NKp46 / NCR1 / CD335 Protein, Fc Tag
NC1-H82F9
Human		 Biotinylated Human NKp46 / NCR1 / CD335 Protein, Fc,Avitag™, premium grade
NC1-M5259
Mouse		 Mouse NKp46 / NCR1 / CD335 Protein, Fc Tag (MALS verified)
NC1-M52H7
Mouse		 Mouse NKp46 / NCR1 / CD335 Protein, His Tag
NC1-M82H5
Mouse		 Biotinylated Mouse NKp46 / NCR1 / CD335 Protein, His,Avitag™
NK6-H82E2
Human		 Biotinylated Human NKp46 / CD335 Protein, His Tag, ultra sensitivity (primary amine labeling)
SCJUR-STF130
Human		 Human NKp46 (Luc) Jurkat Reporter Cell Development Service
ACRO质量管理体系
 
评论(6)
NC1-H52H4|Human NKp46 / NCR1 / CD335 Protein, His Tag (MALS verified)
  1. 177XXXXXXX7
    2. 23人赞
  2. 本次购买蛋白为human-NKP46，用于抗原抗体亲和力筛选检测，使用仪器为octet 分子相互作用仪，从拟合结果上看属于快结合慢解离。
  3. >
  4. 2022-08-05
NC1-C52H4|Cynomolgus NKp46 / NCR1 / CD335 Protein, His Tag (MALS verified)
  1. 166XXXXXXX7
    2. 18人赞
  2. 猴源NKp46抗原与抗体亲和力很好，数据中结合解离图谱很好。
  3. >
  4. 2022-10-17
NC1-H52H4|Human NKp46 / NCR1 / CD335 Protein, His Tag (MALS verified)
  1. 188XXXXXXX5
    2. 15人赞
  2. 采购该蛋白NC1-H52H4，用于抗体人源化的分子筛选表征检测，无论是ELISA 还是 SPR均可以获得稳定的检测结果，推荐使用该目录号的产品。
  3. 2021-11-21
查看更多评论
 

NKp46分子别名

NCR1,LY94,CD335,NK-p46,hNKp46

NKp46分子背景

Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

NKp46临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
IPH-6501 IPH-6501; IPH-65 临床二期 Innate Pharma SA 肿瘤, 非霍奇金淋巴瘤 详情
SAR445514 SAR445514; SAR-445514; IPH6401/SAR'514 临床二期 赛诺菲 淀粉体轻链淀粉样变性, 多发性骨髓瘤 详情
SAR-443579 SAR-443579; SAR443579; SAR'579; IPH6101; IPH-6101 临床二期 赛诺菲 血液疾病, 骨髓增生异常综合征, 母细胞性浆细胞样树突细胞肿瘤, 急性淋巴细胞白血病, B淋巴细胞白血病, 急性髓细胞样白血病 详情

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