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 > 【Siglec-6】

Siglec-6信息

英文名称：Sialic acid-binding Ig-like lectin 6
中文名称：唾液酸结合免疫球蛋白样凝集素-6
靶点别称：CD33 antigen-like 1，CDw327，Obesity-binding protein 1 (OB-BP1)，OBBP1，CD33L，CD33L1，CD327
上市药物数量：0
临床药物数量：2
最高研发阶段：临床二期

Siglec-6产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
SI6-H5256
Human		 Human Siglec-6 / CD327 Protein, Fc Tag
ACRO质量管理体系
 
评论(1)
SI6-H5256|Human Siglec-6 / CD327 Protein, Fc Tag
  1. 619XXXXXXX
    2. 1人赞
  2. The item was expedited very quickly which worked out with our timeline. We are in the process of using the Siglec-6 protein in one of our in-vivo study for immunization. The material itself did not dissolve in complete freund's adjuvant but it was easily made into a fine suspension with the help of some PBS. Overall, I would say the material is easy to work with and the Acro is quick at responding if we have any issues.
  3. 2022-07-13
 

Siglec-6分子别名

SIGLEC6,CD327,CD33L,CD33L1,OBBP1,OB-BP1,CDw327

Siglec-6分子背景

Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1). SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Siglec-6临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
anti-siglec-6 CAR-T cell therapy(Xuzhou Medical University) 临床二期 徐州医科大学 急性髓细胞样白血病 详情
AK-006 AK006 临床一期 Allakos Inc 慢性荨麻疹, 炎性疾病 详情

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