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VSIG4信息

英文名称:V-set and immunoglobulin domain-containing protein 4
中文名称
靶点别称:Protein Z39Ig,CRIg,Z39IG
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

VSIG4产品列表

ACRO质量管理体系
 
评论(2)
VS4-H5226|Human VSIG4 Protein, His Tag
  1. 139XXXXXXX3
  2. 0人赞
  3. 用于抗体筛选,抗原包被以及elisa检测,产品纯度高,包被亲和效果明显,准备后续用于小鼠免疫,希望1-2轮就能检测到高效价
  4. >
  5. 2022-11-08
VS4-H5226|Human VSIG4 Protein, His Tag
  1. 156XXXXXXX7
  2. 0人赞
  3. 购买此蛋白用于小鼠免疫,Elisa和facs检测,小鼠效价高融合效果很好。ELISa和facs曲线做的很漂亮,目前项目进展顺利,感谢他家提供的蛋白
  4. 2021-12-30
 

VSIG4分子别名

VSIG4,CRIg,Z39IG

VSIG4分子背景

V-set and immunoglobulin domain-containing protein 4 (VSIG4) is also known as Protein Z39Ig, is a type I transmembrane glycoprotein. VSIG4 is a B7 family-related protein and an Ig superfamily member. VSIG4 contains two Ig-like (immunoglobulin-like) domains. VSIG4 is abundantly expressed in several fetal tissues. In adult tissues, the highest expression of VSIG4 is in lung and placenta. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. VSIG4 is a phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production.

VSIG4临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
EU-103 EU-103 临床一期 Eutilex 实体瘤, 肿瘤 详情

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