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Neuraminidase (NA)信息

英文名称:Neuraminidase
中文名称:神经氨酸苷酶
靶点别称:Neuraminidase
上市药物数量:4
临床药物数量:5
最高研发阶段:批准上市

Neuraminidase (NA)产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
NE2-V5249
Influenza
Influenza A [A/Darwin/9/2021 (H3N2)] Neuraminidase (NA) Protein, His Tag (MALS verified)
NEE-V5245
Influenza
Influenza B [Austria/1359417/2021] Neuraminidase (NA) Protein, His Tag (MALS & SPR verified)
NEE-V5247
Influenza
Influenza A [Darwin/6/2021] Neuraminidase (NA) Protein, His Tag (SPR verified)
HA1-V5245
Influenza
Influenza A [A/Thailand/1(KAN-1)/2004(H5N1)] Neuraminidase (NA) Protein, His Tag
NE2-V5247
Influenza
Influenza A (A/Sydney/1304/2022) Neuraminidase (NA) Protein, His Tag (MALS verified)
NEE-M697
Human
Monoclonal Anti-Influenza A [A/Thailand/1(KAN-1)/2004] NA (H5N1) Antibody, Human IgG1 (7B8) (MALS verified)
NEE-V5246
Influenza
Influenza B [PHUKET/3073/2013] Neuraminidase (NA) Protein, His Tag (SPR verified)
NEE-V5248
Influenza
Influenza A [Sydney/5/2021] Neuraminidase (NA) Protein, His Tag (SPR verified)
NEE-V5249
Influenza
Influenza A [turkey/Germany-MV/R2472/2014(H5N8)] Neuraminidase (NA) Protein, His Tag
NEE-V524c
Influenza
Influenza A [A/Victoria/4897/2022(H1N1)] Neuraminidase (NA) Protein, His Tag
NEE-V524e
Influenza
Influenza A [Victoria/2570/2019(H1N1)] Neuraminidase (NA) Protein, His Tag
NEE-V524h
Influenza
Influenza A [Guangdong/18SF020(H5N6)] Neuraminidase (NA) Protein, His Tag (MALS & SPR verified)
NEE-V524k
Influenza
Influenza A [Wisconsin/588/2019(H1N1)] Neuraminidase (NA) Protein, His Tag
NEE-V524m
Influenza
Influenza A [Wisconsin/67/2022(H1N1)] Neuraminidase (NA) Protein, His Tag
NEE-V524p
Influenza
Influenza A (A/Georgia/12/2022 CVR-167) Neuraminidase (NA) (A/pdm09 linage) Protein, His Tag
NEE-V524r
Influenza
Influenza B (B/Singapore/INFTT-16-0610/2016) Neuraminidase (NA) Protein, His Tag
NEE-V524u
Influenza
Influenza B (B/Singapore/WUH4618/2021) Neuraminidase (NA) Protein, His Tag
NEE-V524v
Influenza
Influenza A virus (A/Massachusetts/18/2022) NA(H3N2) Protein, His Tag
NEE-V524w
Influenza
Influenza A virus (A/Thailand/8/2022) NA(H3N2) Protein, His Tag
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Neuraminidase (NA)分子别名

NA,Neuraminidase

Neuraminidase (NA)分子背景

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

Neuraminidase (NA)上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验
Laninamivir Octanoate Hydrate 辛酸拉尼米韦 CS-8958; R-118958 批准上市 第一三共株式会社 Inavir Japan 乙型流感病毒感染, 甲型流感病毒感染, 流感病毒感染 null 2010-09-10 甲型流感病毒感染, 流感病毒感染, 哮喘, 乙型流感病毒感染 详情
Zanamivir 扎那米韦 GG-167; GR-121167; GR-121167X; 4-Guanidino-Neu5Ac2en 批准上市 葛兰素史克 依乐韦, Relenza United States 流感病毒感染 Glaxosmithkline Plc 1999-07-26 正黏病毒科感染, 二型糖尿病, 流感病毒感染, 关节痛, 登革热 详情
Oseltamivir Phosphate 磷酸奥司他韦 Ro-64-0796; GS-4104; RO-640796; GS-4104-002; EN-241104; RO-640796/002; GS-4104/002 批准上市 罗氏 Tamiflu, Hanmi Flu, 达菲 Switzerland 流感病毒感染 F. Hoffmann-La Roche Ltd 1999-09-21 特发性血小板减少性紫癜, 甲型流感病毒感染, 流感病毒感染, 禽流感, 肥胖症, 终末期肾脏病 详情
Peramivir Hydrate 帕拉米韦 JNJ-2; BCX-1812; S-021812; RWJ-270201 批准上市 Biocryst Pharmaceuticals Inc 力纬, Alpivab, Rapivab, Rapiacta, Peramiflu Japan 流感病毒感染 null 2010-01-13 咳嗽, 头痛, 肌痛, 肌肉骨骼痛, 疲劳, 甲型流感病毒感染, 流感病毒感染, 发热, 关节痛, 鼻塞, 乙型流感病毒感染, 咽炎 详情

Neuraminidase (NA)临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
AV-5080 AV-5080 临床三期 Viriom Inc 流感病毒感染 详情
HNC042 HNC-042 临床一期 广州市恒诺康医药科技有限公司 甲型流感病毒感染, 流感病毒感染, 乙型流感病毒感染 详情
Oseltamivir/Pimodivir 临床一期 强生 甲型流感病毒感染 详情
Oseltamivir orally disintegrating tablets HY-100209 临床一期 合肥医工医药股份有限公司 甲型流感病毒感染, 乙型流感病毒感染 详情

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