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 > 【SLC1A5】

SLC1A5信息

英文名称:Neutral amino acid transporter B(0)
中文名称
靶点别称:ATB(0),Baboon M7 virus receptor,RD114/simian type D retrovirus receptor,Sodium-dependent neutral amino acid transporter type 2,Solute carrier family 1 member 5,ASCT2,M7V1,RDRC
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

SLC1A5产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
SL5-H5149
Human
Human SLC1A5 Protein, His Tag, TrxA Tag
ACRO质量管理体系
 
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SLC1A5 分子别名

ASCT2,M7V1,RDR,RDRC,ATB(0),AAAT,ASCT2M7VS1,M7V1ATBO,R16,RD114,RDRCFLJ31068

SLC1A5 分子背景

Sodium-dependent amino acids transporter(SLC1A5) that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904).

SLC1A5 前沿进展

SLC1A5临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Idactamab MEDI-7247; INT-001 临床一期 阿斯利康, Medimmune Llc 头颈部鳞状细胞癌, 小细胞肺癌, 弥漫性大B-细胞淋巴瘤, 多发性骨髓瘤, 去势抵抗性前列腺肿瘤, 结直肠癌, 急性髓细胞样白血病, 胰腺导管癌, 非小细胞肺癌 详情

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