英文名称:Hepatitis C virus E2 glycoprotein 中文名称:丙型肝炎病毒包膜糖蛋白E2 靶点别称:
上市药物数量:0 临床药物数量:1 最高研发阶段:临床二期
E2产品咨询
* 此表格只用于收集产品需求咨询,所有信息将严格保密。
评论(0)
E2 分子别名
E2
E2 分子背景
Glycoprotein E2 is an approximately 50 kDa viral envelope protein encoded by the hepatitis C virus (HCV) genome. HCV infection often progresses to severe, liver-associated diseases, such as cirrhosis, steatosis, and hepatocellular carcinoma. Both E1 and E2 are essential for infectivity, with E2 possessing the binding sites for the entry receptors CD81 and SCARB1.Moreover, glycoprotein E2 is BDCA-2 ligand and acts as an inhibitor of IFN production by plasmacytoid dendritic cells.