微电极阵列（MEA）服务

MEA检测服务的主要技术参数

MEA检测服务的主要技术参数

Maestro Edge MEA
检测系统

大脑类器官
产生自发峰值和突发信号

心脏类器官
的心电图测试

选择ACROBiosystems百普赛斯 MEA服务的理由

通过MEA验证多巴胺能神经元自发放电活性

This data set highlights the intrinsic activity of our Human iPSC-Derived Dopamine Neurons (Cat. No. CIPC-DDC001) cultured on an MEA plate. The neurons exhibit robust spontaneous firing, as visualized in the accompanying heatmap video. The raster plot clearly shows regular network burst firing patterns, indicative of well-coordinated neuronal activity. The photo of the neurons on the MEA plate further confirms the successful culture and network formation, making this data a powerful demonstration of their functional connectivity and suitability for neurophysiological studies.

通过MEA验证不同剂量氟哌啶醇对神经元放电活动的影响

This data set demonstrates the dose-dependent effects of Haloperidol on neuronal firing. Raster plots and associated firing parameters (for Weighted Mean Firing Rate, Number of Bursts, Burst Duration, Burst Frequency, and Number of Network Bursts, n = 2) are presented for varying Haloperidol concentrations. At 0.1 μM, the firing activity is enhanced, while at 1 μM, the activity diminishes. At 10 μM, the firing is nearly abolished. These results are consistent with findings from Yokoi et al. (2019), where Haloperidol is known to inhibit D2 receptors at low doses and 5-HT2 receptors at high doses (Tyler et al., 2017). This confirms that the relevant receptors in our Human iPSC-Derived Dopamine Neurons (Cat. No. CIPC-DDC001) are functioning normally, underscoring their utility in drug screening and neurotoxicity studies.