膜杰作
Star Staining
ViruStop
Aneuro
ComboX
ActiveMax
GENPower
ClinMax
SARS-CoV-2试剂盒类产品
背景
新型冠状病毒的大流行对世界卫生安全带来了持续的威胁。通过接种新冠疫苗，辅以抗病毒药物治疗的组合应对措施被认为是当前最高效的防控手段之一。值得关注的是，随着新型冠状病毒毒株的不断变异，其强大的传播及免疫逃逸能力给疫情的防控带来了越加严峻的挑战。面对挑战，对基于野生型毒株开发的已有产品进行评估，并在必要时开发针对突变株的新一代疫苗和抗病毒药物已经成为目前的趋势。
酶联免疫吸附测定法 (Enzyme-Linked ImmunoSorbent Assay , ELISA)
是以酶作为标记物，以抗原和抗体之间特异性结合为基础的固相吸附测定方法，具有特异性好、灵敏度高、反应迅速、实验操作简单等特点，常用于具有复杂基质的多种样本定性或定量分析。
Acrobiosystems经过严格的方法学验证，根据CDE指导原则所述应用场景自主研发出新冠相关ELISA检测试剂盒，旨在提供从临床前和临床研究到产品生产质控环节提供全面解决方案，为客户提高开发效率、降低成本的简便工具。
产品特点：
- 可用于新冠野生型及VOCs变异毒株的抗原及抗体；
- 检测标志物涵盖抗原蛋白、中和抗体、总抗、IgG、IgG抗体亚型、IgM抗体等；
- 严格方法学验证及质控，保证批间差、精密度<10%；
- 高通量，2小时内可完成样本快速检测；
- 环境需求低，操作简单；
- 检测标志物涵盖抗原蛋白、中和抗体、总抗、IgG、IgG抗体亚型、IgM抗体等；
- 严格方法学验证及质控，保证批间差、精密度<10%；
- 高通量，2小时内可完成样本快速检测；
- 环境需求低，操作简单；
生产&质控——抗原含量检测
抗原含量检测
产品列表：
| 货号 | 产品描述 | 订购/预购 |
|---|---|---|
| RAS-A010 | SARS-CoV-2 Nucleocapsid Protein Titer Assay Kit | |
| RAS-A020 | SARS-CoV-2 Spike Protein Titer Assay Kit | |
| RAS-A021 | SARS-CoV-2 Spike RBD Titer Assay Kit | |
| RAS-A039 | SARS-CoV-2 Spike Protein ELISA Kit (For Vaccine Development) | |
| RAS-A050 | SARS-CoV-2 Spike RBD ELISA Kit (For Vaccine Development) | |
| RAS-A115 | SARS-CoV-2 Spike Trimer (Wild Type) Specific ELISA Kit (For Vaccine Development) | |
| RAS-A116 | SARS-CoV-2 Spike RBD (Wild Type) Specific ELISA Kit (For Vaccine Development) | |
| RAS-A055 | SARS-CoV-2 Spike Trimer (B.1.617.2) Specific ELISA Kit (For Vaccine Development) | |
| RAS-A092 | SARS-CoV-2 Spike RBD (B.1.617.2) Specific ELISA Kit (For Vaccine Development) | |
| RAS-A081 | SARS-CoV-2 Spike Trimer (B.1.1.529) Specific ELISA Kit (For Vaccine Development) | |
| RAS-A082 | SARS-CoV-2 Spike RBD (B.1.1.529) Specific ELISA Kit (For Vaccine Development) | |
| RAS-A111 | SARS-CoV-2 Spike Trimer (BA.1) Specific ELISA Kit (High Sensitivity) | |
| RAS-A119 | SARS-CoV-2 Spike Trimer (BA.5) ELISA Kit | |
| RAS-A117 | SARS-CoV-2 Spike RBD (BA.4 & BA.5) ELISA Kit | |
| RAS-A118 | SARS-CoV-2 Spike Trimer (BA.4) ELISA Kit |
验证数据：
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经检测，Cat. No. RAS-A082可特异性检测Omicron Spike Trimer抗原(Cat. No. SPD-C522e)，与其他突变S 蛋白抗原不结合。
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SARS-CoV-2 Spike RBD (B.1.1.529) Specific ELISA Kit (For Vaccine Development)(Cat. No. RAS-A082) can specifically detect SARS-CoV-2 Spike RBD, His Tag (B.1.1.529/Omicron) (Cat. No. SPD-C522e), and cannot detect the spike RBD of other strains, inchuding WT、Alpha、Beta、Gamma and Delta.
临床前研究——动物模型检测
免疫原性检测
产品列表：
| 货号 | 预包被抗原 | 产品描述 | 订购/预购 |
|---|---|---|---|
| RAS-T109 | Spike Trimer | Mouse Anti-SARS-CoV-2 (BA.4) Antibody IgG Titer Serologic Assay Kit (Spike Trimer) | |
| RAS-T108 | Spike RBD | Mouse Anti-SARS-CoV-2 (BA.4 & BA.5) Antibody IgG Titer Serologic Assay Kit (Spike RBD) | |
| RAS-T112 | Spike Trimer | Mouse Anti-SARS-CoV-2 (BA.5) Antibody IgG Titer Serologic Assay Kit (Spike Trimer) | |
| RAS-T114 | Spike Trimer | Mouse Anti-SARS-CoV-2 (BA.2.12.1) Antibody IgG Titer Serologic Assay Kit (Spike Trimer) | |
| RAS-T113 | Spike RBD | Mouse Anti-SARS-CoV-2 (BA.2.12.1)) Antibody IgG Titer Serologic Assay Kit (Spike RBD) | |
| RAS-T090 | Spike S1 | Mouse Anti-SARS-CoV-2 (BA.2) Antibody IgG Titer Serologic Assay Kit (Spike S1) | |
| RAS-T088 | Spike RBD | Mouse Anti-SARS-CoV-2 (BA.2) Antibody IgG Titer Serologic Assay Kit (Spike RBD) | |
| RAS-T089 | Spike protein | Mouse Anti-SARS-CoV-2 (BA.2) Antibody IgG Titer Serologic Assay Kit (Spike Trimer) | |
| RAS-T061 | Spike S1 | Mouse Anti-SARS-CoV-2 (B.1.1.529) Antibody IgG Titer Serologic Assay Kit (Spike S1) | |
| RAS-T064 | Spike S1 | Monkey Anti-SARS-CoV-2 (B.1.1.529) Antibody IgG Titer Serologic Assay Kit (Spike S1) | |
| RAS-T059 | Spike RBD | Mouse Anti-SARS-CoV-2 (B.1.1.529) Antibody IgG Titer Serologic Assay Kit (Spike RBD) | |
| RAS-T062 | Spike RBD | Monkey Anti-SARS-CoV-2 (B.1.1.529) Antibody IgG Titer Serologic Assay Kit (Spike RBD) | |
| RAS-T060 | Spike protein | Mouse Anti-SARS-CoV-2 (B.1.1.529) Antibody IgG Titer Serologic Assay Kit (Spike Trimer) | |
| RAS-T063 | Spike protein | Monkey Anti-SARS-CoV-2 (B.1.1.529) Antibody IgG Titer Serologic Assay Kit (Spike Trimer) | |
| RAS-T086 | Spike S1 | Mouse Anti-SARS-CoV-2 (B.1.617.2) Antibody IgG Titer Serologic Assay Kit (Spike S1) | |
| RAS-T091 | Spike RBD | Mouse Anti-SARS-CoV-2 (B.1.617.2) Antibody IgG Titer Serologic Assay Kit (Spike RBD) | |
| RAS-T070 | Spike protein | Mouse Anti-SARS-CoV-2 (B.1.617.2) Antibody IgG Titer Serologic Assay Kit (Spike Trimer) | |
| RAS-T084 | Spike S1 | Mouse Anti-SARS-CoV-2 (B.1.351) Antibody IgG Titer Serologic Assay Kit (Spike S1) | |
| RAS-T045 | Spike S1 | Mouse Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay Kit (Spike S1) | |
| RAS-T047 | Spike S1 | Monkey Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay Kit (Spike S1) | |
| FCM-B02R | Spike RBD | Mouse SARS-CoV-2 Variants total IgG 6-plex Panel (Flow Cytometry Multiplex Bead Assay) | |
| FCM-B03R | Spike RBD | Monkey SARS-CoV-2 Variants total IgG 6-plex Panel (Flow Cytometry Multiplex Bead Assay) | |
| RAS-T018 | Spike RBD | Mouse Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay kit | |
| RAS-T019 | Spike RBD | Monkey Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay Kit (Spike RBD) | |
| RAS-T023 | Spike protein | Mouse Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay Kit (Spike Trimer) | |
| RAS-T046 | Spike protein | Monkey Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay Kit (Spike Trimer) |
验证数据：
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经验证，Cat. No. RAS-T045可用于检测鼠源IgG抗体滴度，滴度值为12800。
临床研究——体液免疫检测
中和抗体滴度检测
产品列表：
| 新冠突变 | 货号 | 产品描述 | 订购/预购 |
|---|---|---|---|
| Wild type | FCM-N04R | SARS-CoV-2 Variants Neutralizing Antibody 6-plex Panel (Flow Cytometry Multiplex Bead Assay) | |
| Wild type | RAS-N022 | Anti-SARS-CoV-2 Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) | |
| Wild type | RAS-N044 | Anti-SARS-CoV-2 Neutralizing Antibody Quantitative Detection Kit (Spike RBD) | |
| Alpha | B.1.1.7 | RAS-N028 | Anti-SARS-CoV-2 (B.1.1.7) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) | |
| Beta | B.1.351 | RAS-N031 | Anti-SARS-CoV-2 (B.1.351) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) | |
| Gamma | P.1 | RAS-N034 | Anti-SARS-CoV-2 (P.1) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) | |
| Delta | B.1.617.2 | RAS-N040 | Anti-SARS-CoV-2 (B.1.617.2) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) | |
| Delta | B.1.617.2 | RAS-N041 | Anti-SARS-CoV-2 (B.1.617.2) Neutralizing Antibody Titer Serologic Assay Kit (Spike Trimer) | |
| Omicron | B.1.1.529 | RAS-N056 | Anti-SARS-CoV-2 (B.1.1.529) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) | |
| Omicron | BA.2 | RAS-N087 | Anti-SARS-CoV-2 (BA.2) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) | |
| Omicron | BA.4 | RAS-N107 | Anti-SARS-CoV-2 (BA.4 & BA.5) Neutralizing Antibody Titer Serologic Assay Kit (Spike RBD) |
>>> 点击查看更多临床研究过程所需更多生物效价评估方案：新冠假病毒及假病毒中和抗体检测服务
验证数据：
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Anti-SARS-COV-2 Neutralizing Antibody Titer Serologic Assay Kit based on WT RBD (Cat. No. RAS-N022), B.1.1.7 RBD (Cat. No. RAS-N028), B.1.351 RBD (Cat. No. RAS-N031) and P.1 RBD (Cat. No. RAS-N034) are used to detect neutralizing antibodies in 56 post-vaccination serum samples in order to evaluate vaccine efficacy against SARS-CoV-2 Variants of Concerns (VOC).
IgG抗体滴度检测
产品列表：
| 货号 | 预包被抗原 | 产品描述 | 订购/预购 |
|---|---|---|---|
| RAS-T057 | Spike RBD | Anti-SARS-CoV-2 (B.1.1.529) Antibody IgG Titer Serologic Assay Kit (Spike RBD) | |
| RAS-T058 | Spike protein | Anti-SARS-CoV-2 (B.1.1.529) Antibody IgG Titer Serologic Assay Kit (Spike Trimer)) | |
| RAS-T043 | Spike Trimer | Anti-SARS-CoV-2 (B.1.617.2) Antibody IgG Titer Serologic Assay Kit (Spike Trimer) | |
| RAS-T032 | Spike RBD | Anti-SARS-CoV-2 (P.1) Antibody IgG Titer Serologic Assay Kit (Spike RBD) | |
| RAS-T033 | Spike protein | Anti-SARS-CoV-2 (P.1) Antibody IgG Titer Serologic Assay Kit (Spike Trimer) | |
| RAS-T030 | Spike protein | Anti-SARS-CoV-2 (B.1.351) Antibody IgG Titer Serologic Assay Kit (Spike Trimer) | |
| RAS-T026 | Spike RBD | Anti-SARS-CoV-2 (B.1.1.7) Antibody IgG Titer Serologic Assay Kit (Spike RBD) | |
| RAS-T027 | Spike protein | Anti-SARS-CoV-2 (B.1.1.7) Antibody IgG Titer Serologic Assay Kit (Spike Trimer) | |
| RAS-T001 | Spike S1 | Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay Kit (Spike S1) | |
| RAS-T095 | Spike S1 | Anti-SARS-CoV-2 Antibody IgG Quantitative and Titer Detection Kit (Spike S1) | |
| FCM-B01R | Spike RBD | SARS-CoV-2 Variants total IgG 6-plex Panel (Flow Cytometry Multiplex Bead Assay) | |
| RAS-T024 | Spike RBD | Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay Kit (Spike RBD) | |
| RAS-T049 | Spike RBD | Anti-SARS-CoV-2 Antibody IgG Quantitative Detection Kit (Spike RBD) | |
| RAS-T093 | Spike RBD | Anti-SARS-CoV-2 Antibody IgG Quantitative and Titer Detection Kit (Spike RBD) | |
| RAS-T025 | Spike protein | Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay Kit (Spike Trimer) | |
| RAS-T048 | Spike protein | Anti-SARS-CoV-2 Antibody IgG Quantitative Detection Kit (Spike Trimer) | |
| RAS-T094 | Spike protein | Anti-SARS-CoV-2 Antibody IgG Quantitative and Titer Detection Kit (Spike Trimer) | |
| RAS-T008 | Nucleocapsid protein | Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay Kit (Nucleocapsid Protein) |
验证数据：
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接种疫苗后的血清用新冠抗体滴度检测试剂盒（Cat.No. RAS-T024）进行验证,可准确测试血清中抗体滴度。经检测，试剂盒批间精密度<10%，批内精密度：<15%。
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IgG抗体定量检测试剂盒（Cat. No. RAS-T048）与WHO国际标准血清 (G, NIBSC code 20/136)相关性良好，可用于新冠疫苗的有效性评估，可用于接种疫苗后血清样本中的IgG抗体定量检测等，能够显著提高疫苗评价的效率和准确度，是对现有疫苗评价方式的重要补充。
ADE/VED风险研究
产品列表：
| 新冠突变 | 货号 | 产品描述 | 订购/预购 |
|---|---|---|---|
| Wild type | RAS-T014 | Anti-SARS-CoV-2 Antibody IgG1 Titer Serologic Assay kit | |
| Wild type | RAS-T015 | Anti-SARS-CoV-2 Antibody IgG2 Titer Serologic Assay kit | |
| Wild type | RAS-T016 | Anti-SARS-CoV-2 Antibody IgG3 Titer Serologic Assay kit | |
| Wild type | RAS-T017 | Anti-SARS-CoV-2 Antibody IgG4 Titer Serologic Assay kit | |
| Wild type | RAS-T098 | Anti-SARS-CoV-2 (Wild Type) Antibody IgA1 Titer Serologic Assay Kit (Spike RBD) | |
| Wild type | RAS-T100 | Anti-SARS-CoV-2 (Wild Type) Antibody IgA2 Titer Serologic Assay Kit (Spike RBD) | |
| Delta | B.1.617.2 | RAS-T077 | Anti-SARS-CoV-2 (B.1.617.2) Antibody IgG1 Titer Serologic Assay Kit (Spike RBD) | |
| Delta | B.1.617.2 | RAS-T078 | Anti-SARS-CoV-2 (B.1.617.2) Antibody IgG3 Titer Serologic Assay Kit (Spike RBD) | |
| Omicron | B.1.1.529 | RAS-T065 | Anti-SARS-CoV-2 (B.1.1.529) Antibody IgG1 Titer Serologic Assay Kit (Spike RBD) | |
| Omicron | B.1.1.529 | RAS-T066 | Anti-SARS-CoV-2 (B.1.1.529) Antibody IgG2 Titer Serologic Assay Kit (Spike RBD) | |
| Omicron | B.1.1.529 | RAS-T067 | Anti-SARS-CoV-2 (B.1.1.529) Antibody IgG3 Titer Serologic Assay Kit (Spike RBD) | |
| Omicron | B.1.1.529 | RAS-T068 | Anti-SARS-CoV-2 (B.1.1.529) Antibody IgG4 Titer Serologic Assay Kit (Spike RBD) | |
| Omicron | B.1.1.529 | RAS-T099 | Anti-SARS-CoV-2 (BA.1) Antibody IgA1 Titer Serologic Assay Kit (Spike RBD) | |
| Omicron | B.1.1.529 | RAS-T101 | Anti-SARS-CoV-2 (BA.1) Antibody IgA2 Titer Serologic Assay Kit (Spike RBD) | |
| Omicron | BA.2 | RAS-T105 | Anti-SARS-CoV-2 (BA.2) Antibody IgA1 Titer Serologic Assay Kit (Spike RBD) | |
| Omicron | BA.2 | RAS-T106 | Anti-SARS-CoV-2 (BA.2) Antibody IgA2 Titer Serologic Assay Kit (Spike RBD) |
验证数据：
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