Fc受体蛋白，抗体药研发好伙伴 - ACROBiosystems百普赛斯生物科技股份有限公司

背景

热门分子

产品优势

验证数据

产品列表

Fc受体产品册下载立即申请
Fc受体免费protocol 点击获取
FcRn Binding Kit 点击试用
FcγRIIIA Binding Kit 点击试用
FcγRI Binding Kit点击试用

背景

治疗性抗体的功效不仅取决于其Fab片段结合靶抗原的活性，还取决于其Fc片段与Fc受体的相互作用。Fc片段与FcRn（FCGRT&B2M）受体的亲和力可以预测抗体的半衰期，而Fc片段和FcγRⅢA（CD16a）的结合会影响抗体依赖的细胞介导的细胞毒性作用（Antibody-Dependent Cell-mediated Cytotoxicity）。因此，优化抗体结构，筛选获得和Fc受体亲和力最理想的抗体，是发展治疗性抗体药物的一个重要途径。

ACROBiosystems公司提供一系列Fc受体产品，包括了FcRn、FcγR及其常见的突变体，以帮助加速抗体药物的开发。同时，基于我司丰富的蛋白产品资源和活性分析经验，您只需提供样品，我们即可为您提供优质SPR&BLI亲和力检测服务，且免费提供实验所需所有高质量Fc受体蛋白！（Fc受体蛋白作为分析物时除外）点击快速咨询 >>

新品推荐：Human Fc gamma RI / CD64 Binding Kit（TR-FRET）， Human FcRn binding Kit (TR-FRET) 现在均已上线，操作简便，灵敏度高，检测快速，结果精准，助力您的药物研发快人一步。

热门分子

Fc受体蛋白产品优势

HEK293细胞表达：实现翻译后修饰及蛋白正确折叠

多种属：Human, Mouse, Cynomolgus/Rhesus macaque, Rat, Porcine, Rabbit, Feline, Bovine，可全面应用于不同种属交叉实验

高纯度：SDS-PAGE验证纯度＞95%，SEC-MALS验证纯度＞90%

低内毒素：<1.0 EU/μg

亲和力经SPR&BLI验证: 活性有保障，免费提供实验方案

高稳定性：严格质控为高批间一致性保驾护航

提供生物素化定点标记蛋白：采用Avitag^™定点标记的生物素化Fc受体蛋白，标记效率高且标记位点专一明确，方便药物开发及工艺优化过程中基于与链霉亲和素结合的ELISA/SPR/BLI检测

验证数据

产品优势

高纯度

为了满足抗体药研发过程中对用于检测和筛选的蛋白质纯度高的需求，我们的QC团队对大多数重组蛋白都同时进行了SDS-PAGE和SEC-MALS分析。值得注意的是，Fc受体的单体形式反映了其天然状态，应该使用单体纯度尽可能高的Fc受体来验证和抗体的亲和力，以避免因聚集效应而产生的结合活性虚高现象。因此，我们通过SEC-MALS检测建立了严格的单体纯度内部控制标准，只有满足标准的批次才会被放行。

: 图1. 经SDS-PAGE验证，Human CD32a (R167), His Tag (Cat. No. CDA-H5221) 纯度高于 95%；经 SEC-MALS 验证，Human CD32a (R167), His Tag (Cat. No. CDA-H5221) 纯度高于 90%，分子量为25-35 kDa。

亲和力经SPR&BLI验证

分子间的相互作用可以通过多种方法检测。传统的ELISA方法不适合检测像CD16和CD32这样的低亲和力受体与抗体的相互作用，而SPR则成为研究Fc受体与抗体亲和力最常用的方法。为了保证我们的Fc受体能够达到预期的性能，我们的QC团队使用Biacore平台对我们大部分产品进行测试。此外，为了满足客户在抗体药研发过程中不同的应用场景，我们同样采用BLI技术进行了亲和力的验证。所有展现在网页上的SPR&BLI数据都免费提供内部实验操作方法供参考。

: 图2. SPR验证，固定在CM5芯片上的Human CD64, His Tag (Cat. No. FCA-H52H1) 可以结合Herceptin ( 赫赛汀单抗 )，亲和常数为4.92 nM ( Biacore 8K )。; 申请SPR Protocol

点击咨询SPR服务

: 图3. SPR验证，将Human FCGRT&B2M Heterodimer Protein (Cat. No. FCM-H5286)通过anti-His抗体固定在CM5芯片上，可以结合Herceptin (赫赛汀单抗)，亲和常数为0.261 μM (Biacore T200)。; 申请SPR Protocol

点击咨询SPR服务

: 图4. BLI验证，将Human CD64, His Tag (SPR & BLI verified) (Cat. No. FCA-H52H1)固定在HIS1K生物传感器上，可以结合Herceptin (赫赛汀单抗)，亲和常数为6.98 nM (ForteBio Octet Red96e)。; 申请BLI Protocol

点击咨询BLI服务

: 图5. BLI验证，将Human FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI verified) (Cat. No. FCN-H52W7)通过生物素化的his antibody 固定在SA传感器上，可以结合Herceptin (赫赛汀单抗)，亲和常数为0.14 μM (ForteBio Octet Red96e)。; 申请BLI Protocol

点击咨询BLI服务

高批间一致性

我们通过采取严格的质量控制措施，以确保产品的批间一致性。如下图所示，被测样品的批间差异很小。

: 图6. SPR验证，固定在CM5芯片上的Human Fc gamma RIIB / CD32b Protein (Cat. No. CDB-H5228)可以结合Rituximab (利妥昔单抗)，亲和常数为10μM (Biacore T200)。; 申请SPR Protocol

点击咨询SPR服务

用相似度评分软件分析可以看到，不同批次的CD32b相似度非常高，体现了高批间一致性。

: 图7. 不同批次的Human Fc gamma RIIB / CD32b ( Cat. No. CDB-H5228 ) 相似度在90%以上。

产品列表

FcRn
FcγRIII(CD16)
FcγRII(CD32)
FcγRI (CD64)
FcγRIV(CD16-2)
FcεR
FcαR1

产品类型	货号	产品描述	订购/预购
Binding kit(TR-FRET)	FRT-01	Human FcRn binding Kit (TR-FRET)	订购
Overexpressing Cell Line	CHEK-ATP079	HEK293/Human FcRn (FCGRT & B2M) Stable Cell Line	订购
Overexpressing Cell Line	CHEK-ATP132	HEK293/FcRn (FCGRT & B2M), GFP Tag Stable Cell Line	订购
Overexpressing Cell Line	SCCHO-ATP193	CHO/Mouse FCGRT-P2A-mGFP&B2M Cell Line Development Service	订购
Overexpressing Cell Line	SCMDC-ATP196	MDCK/Mouse FCGRT-P2A-mGFP&B2M Cell Line Development Service	订购
Protein	FCM-C5284	Cynomolgus / Rhesus macaque FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag (SPR & BLI & MALS verified)	订购
Protein	FCM-C52W8	Canine FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Tag Free (MALS & SPR verified)	订购
Protein	FCM-C52W9	Cynomolgus / Rhesus macaque FcRn / FCGRT&B2M Heterodimer Protein, His Tag (MALS & BLI verified)	订购
Protein	FCM-C82W3	Biotinylated Cynomolgus / Rhesus macaque FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™ (MALS & SPR verified)	订购
Protein	FCM-C82W5	Biotinylated Cynomolgus / Rhesus macaque FcRn Heterodimer Protein, His,Avitag™&Strep II Tag (HPLC&SPR&BLI verified)	订购
Protein	FCM-C82W9	Biotinylated Canine FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™&Tag Free (MALS & SPR verified)	订购
Protein	FCM-H5283	Human FcRn / FCGRT&B2M Heterodimer Protein, Strep Tag&Tag Free (MALS & SPR verified)	订购
Protein	FCM-H5286	Human FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag (SPR & BLI & HPLC-verified)	订购
Protein	FCM-H8286	Biotinylated Human FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag, ultra sensitivity (primary amine labeling) (HPLC & SPR verified)	订购
Protein	FCM-H82W4	Biotinylated Human FcRn / FCGRT&B2M Heterodimer Protein, Avitag™,His Tag&Strep II Tag (SPR & BLI & HPLC verified)	订购
Protein	FCM-H82W7	Biotinylated Human FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™ (MALS & SPR verified)	订购
Protein	FCM-M52W2	Mouse FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Twin-Strep Tag (MALS & BLI verified)	订购
Protein	FCM-M52W8	Mouse FcRn / FCGRT&B2M Heterodimer Protein, His Tag (MALS & BLI verified)	订购
Protein	FCM-M82W5	Biotinylated Mouse FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™ (MALS & BLI verified)	订购
Protein	FCM-M82W6	Biotinylated Mouse FcRn / FCGRT&B2M Heterodimer Protein, Avitag™,His Tag&Twin-Strep Tag (MALS & BLI-verified)	订购
Protein	FCM-P5280	Porcine FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag (MALS & SPR verified)	订购
Protein	FCM-R5287	Rat FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag (MALS & SPR verified)	订购
Protein	FCM-R52W5	Rabbit FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Tag Free (MALS & SPR verified)	订购
Protein	FCM-R82W6	Biotinylated Rabbit FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™&Tag Free (MALS&SPR verified)	订购
Protein	FCM-R82W7	Biotinylated Rat FcRn / FCGRT&B2M Heterodimer Protein, Avitag™,His Tag&Strep II Tag (MALS & SPR verified)	订购
Protein	FCN-B82W3	Biotinylated Bovine FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™ (MALS & SPR verified)	订购
Protein	FCN-F82W3	Biotinylated Feline FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™ (MALS & SPR verified)	订购
Protein	FCN-H52W7	Human FcRn / FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI & MALS verified)	订购

分子	产品类型	货号	产品描述	订购/预购
Fc gamma RIIIA / CD16a	Binding kit(TR-FRET)	FRT-06	Human Fc gamma RIIIA / CD16a (F176) binding Kit (TR-FRET)	订购
Fc gamma RIIIA / CD16a	Binding kit(TR-FRET)	FRT-07	Human Fc gamma RIIIA / CD16a (V176) binding Kit (TR-FRET)	订购
Fc gamma RIIIA / CD16a	Overexpressing Cell Line	SCCHO-ATP059H	CHO/Human CD16a (158V) Stable Cell Line (High Expression) Development Service	订购
Fc gamma RIIIA / CD16a	Overexpressing Cell Line	SCCHO-ATP059L	CHO/Human CD16a (158V) Stable Cell Line (Low Expression) Development Service	订购
Fc gamma RIIIA / CD16a	Overexpressing Cell Line	SCCHO-ATP059M	CHO/Human CD16a (158V) Stable Cell Line (Medium Expression) Development Service	订购
Fc gamma RIIIA / CD16a	Report Cell Line	SCJUR-STF067	Human CD16a (158V) (Luc) Jurkat Reporter Cell Development Service	订购
Fc gamma RIIIA / CD16a	Report Cell Line	SCJUR-STF068	Human CD16a (158F) (Luc) Jurkat Reporter Cell Development Service	订购
Fc gamma RIIIA / CD16a	Protein	CD8-H52H4	Human Fc gamma RIIIA / CD16a (V176) Protein, His Tag (SPR & BLI & MALS verified)	订购
Fc gamma RIIIA / CD16a	Protein	CDA-H5220	Human Fc gamma RIIIA / CD16a (F176) Protein, His Tag (MALS & SPR verified)	订购
Fc gamma RIIIA / CD16a	Protein	CDA-H5290	Human Fc gamma RIIIA / CD16a (V176) Protein, SUMO,His Tag (MALS & BLI verified)	订购
Fc gamma RIIIA / CD16a	Protein	CDA-H52H6	Human Fc gamma RIIIA / CD16a (F176, S197P) Protein, His Tag (MALS&SPR verified)	订购
Fc gamma RIIIA / CD16a	Protein	CDA-H52S1	Human Fc gamma RIIIA / CD16a (V176) Protein, HSA,His Tag (MALS & BLI verified)	订购
Fc gamma RIIIA / CD16a	Protein	CDA-H82E8	Biotinylated Human Fc gamma RIIIA / CD16a (F176) Protein, Avitag™,His Tag (SPR & BLI & MALS verified)	订购
Fc gamma RIIIA / CD16a	Protein	CDA-H82E9	Biotinylated Human Fc gamma RIIIA / CD16a (V176) Protein, Avitag™,His Tag (HPLC & SPR & BLI verified)	订购
Fc gamma RIIIB / CD16b (NA1)	Protein	CDB-H5227	Human Fc gamma RIIIB / CD16b (NA1) Protein, His Tag (SPR & BLI & MALS verified)	订购
Fc gamma RIIIB / CD16b (NA1)	Protein	CDB-H5296	Human Fc gamma RIIIB / CD16b (NA1) Protein, SUMO,His Tag (MALS & BLI-verified)	订购
Fc gamma RIIIB / CD16b (NA1)	Protein	CDB-H82E4	Biotinylated Human Fc gamma RIIIB / CD16b (NA1) Protein, His,Avitag™ (SPR & BLI & MALS verified)	订购
Fc gamma RIIIB / CD16b (NA2)	Protein	CDB-H5222	Human Fc gamma RIIIB / CD16b (NA2) Protein, His Tag (SPR & BLI & MALS verified)	订购
Fc gamma RIIIB / CD16b (NA2)	Protein	CDB-H5283	Human Fc gamma RIIIB / CD16b (NA2) Protein, Strep Tag (MALS & SPR verified)	订购
Fc gamma RIIIB / CD16b (NA2)	Protein	CDB-H5294	Human Fc gamma RIIIB / CD16b (NA2) Protein, SUMO,His Tag (MALS & BLI-verified)	订购
Fc gamma RIIIB / CD16b (NA2)	Protein	CDB-H82Ea	Biotinylated Human Fc gamma RIIIB / CD16b (NA2) Protein, His,Avitag™ (SPR & BLI & MALS verified)	订购
Fc gamma RIII / CD16	Protein	CDA-M52H8	Mouse Fc gamma RIII / CD16 Protein, His Tag (SPR & BLI & MALS verified)	订购
Fc gamma RIII / CD16	Protein	FC6-C52H9	Cynomolgus Fc gamma RIII / CD16 Protein, His Tag (MALS & BLI verified)	订购
Fc gamma RIII / CD16	Protein	FC6-C82E0	Biotinylated Cynomolgus Fc gamma RIII / CD16 Protein, His,Avitag™ (MALS & BLI verified)	订购
Fc gamma RIII / CD16	Protein	FC6-M82E0	Biotinylated Mouse Fc gamma RIII / CD16 Protein, His,Avitag™ (MALS & SPR verified)	订购
Fc gamma RIII / CD16	Protein	FC6-R52H6	Rhesus macaque Fc gamma RIII / CD16 Protein, His Tag (SPR & BLI & MALS verified)	订购

分子	产品类型	货号	产品描述	订购/预购
Fc gamma RIIA / CD32a	Binding kit(TR-FRET)	FRT-04	Human Fc gamma RIIA / CD32a (H167) binding Kit (TR-FRET)	订购
Fc gamma RIIA / CD32a	Binding kit(TR-FRET)	FRT-05	Human Fc gamma RIIA / CD32a (R167) binding Kit (TR-FRET)	订购
Fc gamma RIIA / CD32a	Overexpressing Cell Line	SCCHO-ATP061H	CHO/Human CD32a Stable Cell Line (High Expression) Development Service	订购
Fc gamma RIIA / CD32a	Overexpressing Cell Line	SCCHO-ATP061L	CHO/Human CD32a Stable Cell Line (Low Expression) Development Service	订购
Fc gamma RIIA / CD32a	Overexpressing Cell Line	SCCHO-ATP061M	CHO/Human CD32a Stable Cell Line (Medium Expression) Development Service	订购
Fc gamma RIIA / CD32a	Report Cell Line	SCJUR-STF069	Human CD32a (131H) (Luc) Jurkat Reporter Cell Development Service	订购
Fc gamma RIIA / CD32a	Report Cell Line	SCJUR-STF070	Human CD32a (131R) (Luc) Jurkat Reporter Cell Development Service	订购
Fc gamma RIIA / CD32a	Protein	CD1-H5223	Human Fc gamma RIIA / CD32a (H167) Protein, His Tag (SPR & BLI & MALS verified)	订购
Fc gamma RIIA / CD32a	Protein	CDA-C52H7	Cynomolgus Fc gamma RIIA / CD32a Protein, His Tag (SPR & BLI & MALS verified)	订购
Fc gamma RIIA / CD32a	Protein	CDA-C82E5	Biotinylated Cynomolgus Fc gamma RIIA / CD32a Protein, His,Avitag™ (SPR & BLI & MALS verified)	订购
Fc gamma RIIA / CD32a	Protein	CDA-H5221	Human Fc gamma RIIA / CD32a (R167) Protein, His Tag (MALS & BLI verified)	订购
Fc gamma RIIA / CD32a	Protein	CDA-H5283	Human Fc gamma RIIA / CD32a (R167) Protein, Strep Tag (MALS & SPR verified)	订购
Fc gamma RIIA / CD32a	Protein	CDA-H5284	Human Fc gamma RIIA / CD32a (H167) Protein, Strep Tag (MALS & SPR verified)	订购
Fc gamma RIIA / CD32a	Protein	CDA-H82E5	Biotinylated Human Fc gamma RIIA / CD32a (R167) Protein, His,Avitag™ (MALS & SPR verified)	订购
Fc gamma RIIA / CD32a	Protein	CDA-H82E6	Biotinylated Human Fc gamma RIIA / CD32a (H167) Protein, Avitag™,His Tag (SPR & BLI & MALS verified)	订购
Fc gamma RIIA / CD32a	Protein	CDA-R52H4	Rhesus macaque Fc gamma RIIA / CD32a Protein, His Tag (SPR & BLI & MALS verified)	订购
Fc gamma RIIA / CD32a	Protein	CDA-R52H5	Rat Fc gamma RIIA / CD32a Protein, His Tag (MALS & SPR verified)	订购
Fc gamma RIIB / CD32b	Overexpressing Cell Line	SCCHO-ATP060H	CHO/Human CD32b Stable Cell Line (High Expression) Development Service	订购
Fc gamma RIIB / CD32b	Overexpressing Cell Line	SCCHO-ATP060L	CHO/Human CD32b Stable Cell Line (Low Expression) Development Service	订购
Fc gamma RIIB / CD32b	Overexpressing Cell Line	SCCHO-ATP060M	CHO/Human CD32b Stable Cell Line (Medium Expression) Development Service	订购
Fc gamma RIIB / CD32b	Report Cell Line	SCJUR-STF071	Human CD32b (Luc) Jurkat Reporter Cell Development Service	订购
Fc gamma RIIB / CD32b	Protein	CDB-C5224	Cynomolgus Fc gamma RIIB / CD32b Protein, His Tag (MALS & SPR verified)	订购
Fc gamma RIIB / CD32b	Protein	CDB-C82E4	Biotinylated Cynomolgus Fc gamma RIIB / CD32b Protein, His,Avitag™ (SPR & BLI & MALS verified)	订购
Fc gamma RIIB / CD32b	Protein	CDB-M52H7	Mouse Fc gamma RIIB / CD32b Protein, His Tag (SPR & BLI & MALS verified)	订购
Fc gamma RIIB / CD32b	Protein	CDB-M82E8	Biotinylated Mouse Fc gamma RIIB / CD32b Protein, Avitag™,His Tag (SPR & BLI & MALS verified)	订购
Fc gamma RIIB / CD32b	Protein	CDB-R52H3	Rat Fc gamma RIIB / CD32b Protein, His Tag (MALS verified)	订购
Fc gamma RIIB/C / CD32b/c	Protein	CDB-H5228	Human Fc gamma RIIB/C (CD32b/c) Protein, His Tag (SPR & BLI & MALS verified)	订购
Fc gamma RIIB/C / CD32b/c	Protein	CDB-H5284	Human Fc gamma RIIB/C (CD32b/c) Protein, Strep Tag (MALS & SPR verified)	订购
Fc gamma RIIB/C / CD32b/c	Protein	CDB-H5298	Human Fc gamma RIIB/C (CD32b/c) Protein, SUMO,His Tag (MALS & BLI verified)	订购
Fc gamma RIIB/C / CD32b/c	Protein	CDB-H52S9	Human Fc gamma RIIB/C (CD32b/c) Protein, HSA,His Tag (MALS & BLI verified)	订购
Fc gamma RIIB/C / CD32b/c	Protein	CDB-H82E0	Biotinylated Human Fc gamma RIIB/C (CD32b/c) Protein, Avitag™,His Tag (SPR & BLI & MALS verified)	订购

分子	产品类型	货号	产品描述	订购/预购
Fc gamma RI / CD64	Binding kit(TR-FRET)	FRT-03	Human Fc gamma RI / CD64 binding Kit (TR-FRET)	订购
Fc gamma RI / CD64	Overexpressing Cell Line	SCCHO-ATP062H	CHO/Human CD64 Stable Cell Line (High Expression) Development Service	订购
Fc gamma RI / CD64	Overexpressing Cell Line	SCCHO-ATP062L	CHO/Human CD64 Stable Cell Line (Low Expression) Development Service	订购
Fc gamma RI / CD64	Overexpressing Cell Line	SCCHO-ATP062M	CHO/Human CD64 Stable Cell Line (Medium Expression) Development Service	订购
Fc gamma RI / CD64	Report Cell Line	SCJUR-STF072	Human CD64 (Luc) Jurkat Reporter Cell Development Service	订购
Fc gamma RI / CD64	Protein	CD4-M5227	Mouse Fc gamma RI / CD64 Protein, His Tag (MALS & BLI verified)	订购
Fc gamma RI / CD64	Protein	CD4-M82E7	Biotinylated Mouse Fc gamma RI / CD64 Protein, His,Avitag™ (MALS & SPR verified)	订购
Fc gamma RI / CD64	Protein	CD4-R52H3	Rat Fc gamma RI / CD64 Protein, His Tag (MALS verified)	订购
Fc gamma RI / CD64	Protein	FCA-C52H6	Cynomolgus Fc gamma RI / CD64 Protein, His Tag (MALS & SPR verified)	订购
Fc gamma RI / CD64	Protein	FCA-C52H8	Canine Fc gamma RI / CD64 Protein, His Tag (MALS & SPR verified)	订购
Fc gamma RI / CD64	Protein	FCA-C82E8	Biotinylated Cynomolgus Fc gamma RI / CD64 Protein, His,Avitag™ (MALS & BLI verified)	订购
Fc gamma RI / CD64	Protein	FCA-H52H1	Human Fc gamma RI / CD64 Protein, His Tag (SPR & BLI & MALS verified)	订购
Fc gamma RI / CD64	Protein	FCA-H82E8	Biotinylated Human Fc gamma RI / CD64 Protein, His,Avitag™ (SPR & BLI & MALS verified)	订购

分子	产品类型	货号	产品描述	订购/预购
Fc gamma RIV / CD16-2	Protein	FC4-M52H3	Mouse Fc gamma RIV / CD16-2 Protein, His Tag (MALS verified)	订购
Fc gamma RIV / CD16-2	Protein	FC4-M82E8	Biotinylated Mouse Fc gamma RIV / CD16-2 Protein, His,Avitag™ (HPLC & BLI verified)	订购

分子	产品类型	货号	产品描述	订购/预购
Fc epsilon RI alpha	Inhibitor Screening ELISA	EP-169	Fc epsilon RI alpha [Biotinylated] : IgE Fc Inhibitor Screening ELISA Kit	订购
Fc epsilon RI alpha	Protein	FCA-C5255	Cynomolgus Fc epsilon RI alpha Protein, Fc Tag (BLI verified)	订购
Fc epsilon RI alpha	Protein	FCA-C52H9	Cynomolgus Fc epsilon RI alpha Protein, His Tag (SPR verified)	订购
Fc epsilon RI alpha	Protein	FCA-H5228	Human Fc epsilon RI alpha Protein, His Tag (MALS verified)	订购
Fc epsilon RI alpha	Protein	FCA-H5259	Human Fc epsilon RI alpha Protein, Fc Tag (MALS & BLI verified)	订购
Fc epsilon RI alpha	Protein	FCA-H82E3	Biotinylated Human Fc epsilon RI alpha Protein, His,Avitag™ (MALS & BLI verified)	订购

分子	产品类型	货号	产品描述	订购/预购
CD89	Protein	CD9-H52Ha	Human CD89 / FCAR Protein, His Tag (MALS verified)	订购

Fc受体相关分子

IgG Fc IgG1 Fc IgG2 Fc IgG2a Fc IgG2b Fc IgG4 Fc IgG3 Fc IgE Fc FCRL5

部分引用文献

Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention

Authors: Kielau Kisalu, Neville et al.

Journal: JCI Insight 2020

Cited Product: FCM-H5286, FCM-C5284, FCM-M82W5

Application: BLI

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Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody

Authors: Asokan M, Dias J, Liu C, et al

Cited Product: FCM-C5284

Journal: Proc Natl Acad Sci U S A2020

Application: BLI

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Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity

Authors: Simonov V, et al

Cited Product: FCM-H5286

Journal: Biologicals 2019

Application: BLI

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Engineered antibody Fc variants for enhanced serum half life

Authors: G Georgiou, et al

Cited Product: FCM-H5286

Journal: US20190048078A1 2019

Application: SPR

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Comparative studies of the serum half-life extension of a protein via site-specific conjugation to a species-matched or -mismatched albumin.

Authors: Yang B, et al.

Cited Product: FCM-H5286, FCM-M52W2

Journal: Biomater Sci 2018

Application: ELISA

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Unidirectional transport of IgG by neonatal Fc receptor in human thyrocytes varies across different IgG subclasses

Authors: Zhao C, et al.

Cited Product: FCM-H5286

Journal: Mol Cell Endocrinol 2018

Application: SPR

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Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody

Authors: Kenniston JA, et al.

Cited Product: FCM-H5286 FCM-M52W2, FCM-R5287, FCM-C5284

Journal: J Biol Chem 2017

Application: ELISA & SPR

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Single chain Fc-dimer-human growth hormone fusion protein for improved drug delivery

Authors: Li Zhou, et al.

Cited Product: FCM-H5286

Journal: Biomaterials 2016

Application: SPR

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CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD + and NMN levels

Authors: Chini CCS, Peclat TR, Warner GM, et al.

Cited Product: FC4-M52H3, CD4-M5227

Journal: Nature metabolism 2020

Application: Binding Assay

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Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity

Authors: Simonov V, et al

Cited Product: CDB-H5228, CDA-H5221, CDA-H5220, CDB-H5222

Journal: Biologicals 2019

Application: SPR

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Identification of anti-CD16a single domain antibodies and their application in bispecific antibodies

Authors: Zhao Y, et al

Cited Product: CD8-H52H4

Journal: Cancer Biol Ther 2019

Application: immunization

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Charge variant analysis of proposed biosimilar to Trastuzumab

Authors: Dakshinamurthy P, et al.

Cited Product: CD8-H52H4

Journal: Biologicals 2017

Application: SPR

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Sialylation of immunoglobulin E is a determinant of allergic pathogenicity

Authors: Kai Ting C Shade, et al

Cited Product: CD3-H5249

Journal: Nature 2020

Application: BLI

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